Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.

DL, Paterson; WC, Ko; Gottberg A, Von; JM, Casellas; L, Mulazimoglu; KP, Klugman; RA, Bonomo; LB, Rice; JG, McCormack; VL, Yu

doi:10.1128/jcm.39.6.2206-2212.2001

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Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.

Shared by NobleBlocks on Jun 1, 2001 • 12:00 AM UTC

Authors:

Paterson DL

Ko WC

Von Gottberg A

Abstract

Although extended-spectrum beta-lactamases (ESBLs) hydrolyze cephalosporin antibiotics, some ESBL-producing organisms are not resistant to all cephalosporins when tested in vitro. Some authors have suggested that screening klebsiellae or Escherichia coli for ESBL production is not clinically necessa...

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