Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.

I Russell, Jon; J Mease, Philip; R Smith, Timothy; K Kajdasz, Daniel; M Wohlreich, Madelaine; J Detke, Michael; J Walker, Daniel; S Chappell, Amy; M Arnold, Lesley

doi:10.1016/j.pain.2008.02.024

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Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.

Published in Pain • Jun 1, 2008

Authors:

Jon I Russell

Philip J Mease

Timothy R Smith

Abstract

The primary objectives of this study were to assess the efficacy and safety of duloxetine for reducing pain severity in fibromyalgia patients with or without current major depressive disorder. This was a 6-month, multicenter, randomized, double-blind, placebo-controlled study. In total, 520 patients...

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