Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia.

DL, Paterson; L, Mulazimoglu; JM, Casellas; WC, Ko; H, Goossens; Gottberg A, Von; S, Mohapatra; GM, Trenholme; KP, Klugman; JG, McCormack; VL, Yu

doi:10.1086/313719

Public

Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia.

Shared by NobleBlocks on Mar 1, 2000 • 12:00 AM UTC

Authors:

Paterson DL

Mulazimoglu L

Casellas JM

Abstract

A prospective study of Klebsiella pneumoniae bacteremia was performed in 12 hospitals in 7 countries. Of 452 episodes of bacteremia, 25 (5.5%) were caused by K. pneumoniae that was resistant in vitro to ciprofloxacin. Extended-spectrum beta-lactamase (ESBL) production was detected in 15 (60%) of 25 ...

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