A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry.

P, Yin; D, Wan; C, Zhao; J, Chen; X, Zhao; W, Wang; X, Lu; S, Yang; J, Gu; G, Xu

doi:10.1039/b820224a

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A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry.

Shared by NobleBlocks on Jun 17, 2009 • 12:00 AM UTC

Authors:

Yin P

Wan D

Zhao C

Abstract

Liver cirrhosis and hepatocellular carcinoma (HCC) are fatal sequelaes of chronic hepatitis B in China. The sera from HCC and cirrhosis were profiled by rapid resolution liquid chromatography coupled with quadrupole time-of-flight (Q-TOF) mass spectrometry. Reversed-phased (RP) liquid chromatography...

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