Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy.

Eller, Kathrin; Kirsch, Alexander; M Wolf, Anna; Sopper, Sieghart; Tagwerker, Andrea; Stanzl, Ursula; Wolf, Dominik; Patsch, Wolfgang; R Rosenkranz, Alexander; Eller, Philipp

doi:10.2337/db11-0358

Public

Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy.

Shared by NobleBlocks on Nov 1, 2011 • 12:00 AM UTC

Authors:

Kathrin Eller

Alexander Kirsch

Anna M Wolf

Abstract

OBJECTIVE: To assess the potential role of FoxP3-expressing regulatory T cells (Tregs) in reversing obesity-linked insulin resistance and diabetic nephropathy in rodent models and humans. RESEARCH DESIGN AND METHODS: To characterize the role of Tregs in insulin resistance, human visceral adipose tis...

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