Association of HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians.

TY, Mehta; LM, Prajapati; B, Mittal; CG, Joshi; JJ, Sheth; DB, Patel; DM, Dave; RK, Goyal

doi:10.4103/0378-6323.57718

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Association of HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians.

Shared by NobleBlocks on Nov 1, 2009 • 12:00 AM UTC

Authors:

Mehta TY

Prajapati LM

Mittal B

Abstract

<h4>Background</h4>Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA)-B*1502 and carbamazepine-induced SJS in Han Chi...

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