A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma.

Khaenam, Prasong; Rinchai, Darawan; C Altman, Matthew; Chiche, Laurent; Buddhisa, Surachat; Kewcharoenwong, Chidchamai; Suwannasaen, Duangchan; Mason, Michael; Whalen, Elizabeth; Presnell, Scott; Susaengrat, Wattanachai; O'Brien, Kimberly; Nguyen, Quynh-Ahn; Gersuk, Vivian; S Linsley, Peter; Lertmemongkolchai, Ganjana; Chaussabel, Damien

doi:10.1186/1479-5876-12-65

Public

A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma.

Shared by NobleBlocks on Mar 11, 2014 • 12:00 AM UTC

Authors:

Prasong Khaenam

Darawan Rinchai

Matthew C Altman

Abstract

BACKGROUND: There are diverse molecules present in blood plasma that regulate immune functions and also present a potential source of disease biomarkers and therapeutic targets. Genome-wide profiling has become a powerful method for assessing immune responses on a systems scale, but technologies tha...

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