Phase III trial of pemetrexed plus best supportive care compared with best supportive care in previously treated patients with advanced malignant pleural mesothelioma.

J, Jassem; R, Ramlau; A, Santoro; W, Schuette; A, Chemaissani; S, Hong; J, Blatter; S, Adachi; A, Hanauske; C, Manegold

doi:10.1200/jco.2006.09.9887

Public

Phase III trial of pemetrexed plus best supportive care compared with best supportive care in previously treated patients with advanced malignant pleural mesothelioma.

Shared by NobleBlocks on Apr 1, 2008 • 12:00 AM UTC

Authors:

Jassem J

Ramlau R

Santoro A

Abstract

<h4>Purpose</h4>This multicenter, phase III study compared overall survival (OS) of second-line pemetrexed plus best supportive care (BSC) versus BSC alone in patients with advanced malignant pleural mesothelioma (MPM). Secondary end points included response rate, progression-free survival (PFS), ti...

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