Predictive Biomarker Profiling of > 6000 Breast Cancer Patients Shows Heterogeneity in TNBC, With Treatment Implications.

SZ, Millis; Z, Gatalica; J, Winkler; S, Vranic; J, Kimbrough; S, Reddy; JA, O'Shaughnessy

doi:10.1016/j.clbc.2015.04.008

Public

Predictive Biomarker Profiling of > 6000 Breast Cancer Patients Shows Heterogeneity in TNBC, With Treatment Implications.

Shared by NobleBlocks on Apr 28, 2015 • 12:00 AM UTC

Authors:

Millis SZ

Gatalica Z

Winkler J

Abstract

<h4>Background</h4>Triple-negative breast cancer (TNBC) is an aggressive disease without established targeted treatment options for patients with metastatic disease. This study was undertaken to evaluate potentially actionable biomarkers in a large cohort of TNBC and compare them with non-TNBCs.<h4>...

Subject

Immunohistochemistry

Sequencing

in situ Hybridization

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