antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences.

MH, Medema; K, Blin; P, Cimermancic; Jager V, de; P, Zakrzewski; MA, Fischbach; T, Weber; E, Takano; R, Breitling

doi:10.1093/nar/gkr466

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antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences.

Published in Nucleic acids research • Jun 14, 2011

Authors:

Medema MH

Blin K

Cimermancic P

Abstract

Bacterial and fungal secondary metabolism is a rich source of novel bioactive compounds with potential pharmaceutical applications as antibiotics, anti-tumor drugs or cholesterol-lowering drugs. To find new drug candidates, microbiologists are increasingly relying on sequencing genomes of a wide var...

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