RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

M Lau, Christina; Broughton, Courtney; S Tabor, Abigail; Akira, Shizuo; A Flavell, Richard; J Mamula, Mark; R Christensen, Sean; J Shlomchik, Mark; A Viglianti, Gregory; R Rifkin, Ian; Marshak-Rothstein, Ann

doi:10.1084/jem.20050630

Public

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

Shared by NobleBlocks on Nov 7, 2005 • 12:00 AM UTC

Authors:

Christina M Lau

Courtney Broughton

Abigail S Tabor

Abstract

Previous studies (Leadbetter, E.A., I.R. Rifkin, A.H. Hohlbaum, B. Beaudette, M.J. Shlomchik, and A. Marshak-Rothstein. 2002. Nature. 416:603-607; Viglianti, G.A., C.M. Lau, T.M. Hanley, B.A. Miko, M.J. Shlomchik, and A. Marshak-Rothstein. 2003. Immunity. 19:837-847) established the unique capacity ...

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