ProBiS algorithm for detection of structurally similar protein binding sites by local structural alignment.

Konc, Janez; Janezic, Dusanka

doi:10.1093/bioinformatics/btq100

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ProBiS algorithm for detection of structurally similar protein binding sites by local structural alignment.

Shared by NobleBlocks on May 1, 2010 • 12:00 AM UTC

Authors:

Janez Konc

Dusanka Janezic

Abstract

MOTIVATION: Exploitation of locally similar 3D patterns of physicochemical properties on the surface of a protein for detection of binding sites that may lack sequence and global structural conservation. RESULTS: An algorithm, ProBiS is described that detects structurally similar sites on protein su...

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