Human metabolic profiles are stably controlled by genetic and environmental variation.

Nicholson, George; Rantalainen, Mattias; D Maher, Anthony; V Li, Jia; Malmodin, Daniel; R Ahmadi, Kourosh; H Faber, Johan; B Hallgrímsdóttir, Ingileif; Barrett, Amy; Toft, Henrik; Krestyaninova, Maria; Viksna, Juris; Guha Neogi, Sudeshna; Dumas, Marc-Emmanuel; Sarkans, Ugis; Molpage Consortium, The; W Silverman, Bernard; Donnelly, Peter; K Nicholson, Jeremy; Allen, Maxine; T Zondervan, Krina; C Lindon, John; D Spector, Tim; I McCarthy, Mark; Holmes, Elaine; Baunsgaard, Dorrit; C Holmes, Chris

doi:10.1038/msb.2011.57

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Human metabolic profiles are stably controlled by genetic and environmental variation.

Shared by NobleBlocks on Aug 30, 2011 • 12:00 AM UTC

Authors:

George Nicholson

Mattias Rantalainen

Anthony D Maher

Abstract

¹H Nuclear Magnetic Resonance spectroscopy (¹H NMR) is increasingly used to measure metabolite concentrations in sets of biological samples for top-down systems biology and molecular epidemiology. For such purposes, knowledge of the sources of human variation in metabolite concentrations is valuable...

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