Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study.

M, Valgimigli; G, Campo; Cesare N, de; E, Meliga; P, Vranckx; A, Furgieri; DJ, Angiolillo; M, Sabatè; M, Hamon; A, Repetto; S, Colangelo; S, Brugaletta; G, Parrinello; G, Percoco; R, Ferrari

doi:10.1161/circulationaha.108.833236

Public

Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study.

Shared by NobleBlocks on Jun 15, 2009 • 12:00 AM UTC

Authors:

Valgimigli M

Campo G

de Cesare N

Abstract

<h4>Background</h4>Inhibition of platelet aggregation after aspirin or clopidogrel intake varies greatly among patients, and previous studies have suggested that poor response to oral antiplatelet agents may increase the risk of thrombotic events, especially after coronary angioplasty. Whether this ...

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