Recurrence Pattern After Temozolomide Concomitant With and Adjuvant to Radiotherapy in Newly Diagnosed Patients With Glioblastoma: Correlation With <i>MGMT</i> Promoter Methylation Status

A. Brandes, Alba; Tosoni, Alicia; Franceschi, Enrico; Sotti, Guido; Frezza, Giampiero; Amistà, Pietro; Morandi, Luca; Spagnolli, Federica; Ermani, Mario

doi:10.1200/jco.2008.19.4969

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Recurrence Pattern After Temozolomide Concomitant With and Adjuvant to Radiotherapy in Newly Diagnosed Patients With Glioblastoma: Correlation With <i>MGMT</i> Promoter Methylation Status

Shared by NobleBlocks on Mar 10, 2009 • 12:00 AM UTC

Authors:

Alba A. Brandes

Alicia Tosoni

Enrico Franceschi

Abstract

Purpose The aim of the present study was to evaluate factors predicting the recurrence pattern after the administration of temozolomide (TMZ), initially concurrent with radiotherapy (RT) and subsequently as maintenance therapy, which has become standard treatment for patients with newly diagnosed gl...

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