ATP stimulates chemically sensitive and sensitizes mechanically sensitive afferents

Li, Jianhua; I. Sinoway, Lawrence

doi:10.1152/ajpheart.00395.2002

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ATP stimulates chemically sensitive and sensitizes mechanically sensitive afferents

Published in American Journal of Physiology-Heart and Circulatory Physiology • Dec 1, 2002

Authors:

Jianhua Li

Lawrence I. Sinoway

Abstract

We examined whether ATP stimulation of P2X purinoceptors would raise blood pressure in decerebrate cats. Femoral arterial injection of the P2X receptor agonist alpha,beta-methylene ATP into the blood supply of the triceps surae muscle induced a dose-dependent increase in arterial blood pressure. The...

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P2 receptor

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