Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells.

J, Wu; Z, Meng; M, Jiang; R, Pei; M, Trippler; R, Broering; A, Bucchi; JP, Sowa; U, Dittmer; D, Yang; M, Roggendorf; G, Gerken; M, Lu; JF, Schlaak

doi:10.1002/hep.22751

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Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells.

Shared by NobleBlocks on Apr 1, 2009 • 12:00 AM UTC

Authors:

Wu J

Meng Z

Jiang M

Abstract

<h4>Unlabelled</h4>We have previously shown that Toll-like receptor (TLR)-activated murine nonparenchymal liver cells [(NPC); Kupffer cells (KC), liver sinusoidal endothelial cells (LSEC)] can suppress hepatitis B virus (HBV) replication. Therefore, the aim of this study was to investigate whether H...

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