Final Trial Report of Sentinel-Node Biopsy versus Nodal Observation in Melanoma

Morton, D.; F. Thompson, John; Cochran, A.; Mozzillo, N.; Nieweg, O.; Roses, D.; J. Hoekstra, H.; Karakousis, C.; Puleo, C.; Coventry, B.; Kashani-Sabet, M.; M. Smithers, B.; Paul, Eberhard; Kraybill, W.; Mckinnon, J.; Wang, He-jing; Elashoff, R.; Faries, M.

doi:10.1056/NEJMoa1310460

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Final Trial Report of Sentinel-Node Biopsy versus Nodal Observation in Melanoma

Shared by NobleBlocks on Feb 12, 2014 • 12:00 AM UTC

Authors:

D. Morton

John F. Thompson

A. Cochran

Abstract

Background Sentinel-node biopsy, a minimally invasive procedure for regional melanoma staging, was evaluated in a phase 3 trial. Methods We evaluated outcomes in 2001 patients with primary cutaneous melanomas randomly assigned to undergo wide excision and nodal observation, with lymphadenectomy for ...

Subject

Medicine

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