Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection.

Liu, Bin; Zhang, Deyuan; Xu, Ruifeng; Xu, Jinghao; Wang, Xiaolong; Chen, Qingcai; Dong, Qiwen; Chou, Kuo-Chen

doi:10.1093/bioinformatics/btt709

Public

Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection.

Shared by NobleBlocks on Feb 15, 2014 • 12:00 AM UTC

Authors:

Bin Liu

Deyuan Zhang

Ruifeng Xu

Abstract

MOTIVATION: Owing to its importance in both basic research (such as molecular evolution and protein attribute prediction) and practical application (such as timely modeling the 3D structures of proteins targeted for drug development), protein remote homology detection has attracted a great deal of i...

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