Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery.

GI, Juhl; SE, Norholt; E, Tonnesen; O, Hiesse-Provost; TS, Jensen

doi:10.1016/j.ejpain.2005.06.004

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Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery.

Shared by NobleBlocks on Aug 8, 2005 • 12:00 AM UTC

Authors:

Juhl GI

Norholt SE

Tonnesen E

Abstract

<h4>Background</h4>The recommended dose for intravenous (IV) paracetamol injection in adults is 1g, however pharmacokinetic and pharmacodynamic findings suggest that a better analgesia could be obtained with a 2 g starting dose.<h4>Methods</h4>A single-centre, randomised, double-blind, placebo-contr...

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