SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.

A, Mozos; C, Royo; E, Hartmann; Jong D, De; C, Baró; A, Valera; K, Fu; DD, Weisenburger; J, Delabie; SS, Chuang; ES, Jaffe; C, Ruiz-Marcellan; S, Dave; L, Rimsza; R, Braziel; RD, Gascoyne; F, Solé; A, López-Guillermo; D, Colomer; LM, Staudt; A, Rosenwald; G, Ott; P, Jares; E, Campo

doi:10.3324/haematol.2009.010264

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SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.

Shared by NobleBlocks on Nov 1, 2009 • 12:00 AM UTC

Authors:

Mozos A

Royo C

Hartmann E

Abstract

<h4>Background</h4>Cyclin D1-negative mantle cell lymphoma is difficult to distinguish from other small B-cell lymphomas. The clinical and pathological characteristics of patients with this form of lymphoma have not been well defined. Overexpression of the transcription factor SOX11 has been observe...

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