One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial.

C Bunck, Mathijs; Diamant, Michaela; Cornér, Anja; Eliasson, Bjorn; L Malloy, Jaret; M Shaginian, Rimma; Deng, Wei; M Kendall, David; Taskinen, Marja-Riitta; Smith, Ulf; Yki-Järvinen, Hannele; J Heine, Robert

doi:10.2337/dc08-1797

Public

One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial.

Shared by NobleBlocks on May 1, 2009 • 12:00 AM UTC

Authors:

Mathijs C Bunck

Michaela Diamant

Anja Cornér

Abstract

OBJECTIVE: Traditional blood glucose-lowering agents do not sustain adequate glycemic control in most type 2 diabetic patients. Preclinical studies with exenatide have suggested sustained improvements in beta-cell function. We investigated the effects of 52 weeks of treatment with exenatide or insul...

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