A Variant in
            <i>LDLR</i>
            Is Associated With Abdominal Aortic Aneurysm

T. Bradley, Declan; E. Hughes, Anne; A. Badger, Stephen; T. Jones, Gregory; C. Harrison, Seamus; J. Wright, Benjamin; Bumpstead, Suzannah; F. Baas, Annette; Grétarsdóttir, Sólveig; Burnand, Kevin; H. Child, Anne; E. Clough, Rachel; Cockerill, Gillian; Hafez, Hany; Julian A. Scott, D.; A.S. Ariëns, Robert; Johnson, Anne; Sohrabi, Soroush; Smith, Alberto; M. Thompson, Matthew; M. van Bockxmeer, Frank; Waltham, Matthew; E. Matthíasson, Stefán; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; D. Blankensteijn, Jan; A.W. Teijink, Joep; Wijmenga, Cisca; de Graaf, Jacqueline; A. Kiemeney, Lambertus; B. Wild, John; Edkins, Sarah; Gwilliam, Rhian; E. Hunt, Sarah; Potter, Simon; S. Lindholt, Jes; Golledge, Jonathan; E. Norman, Paul; van Rij, Andre; T. Powell, Janet; Eriksson, Per; Stefánsson, Kári; R. Thompson, John; E. Humphries, Steve; D. Sayers, Robert; Deloukas, Panos; J. Samani, Nilesh; J. Bown, Matthew

doi:10.1161/circgenetics.113.000165

Public

A Variant in <i>LDLR</i> Is Associated With Abdominal Aortic Aneurysm

Published in Circulation: Cardiovascular Genetics • Oct 1, 2013

Authors:

Declan T. Bradley

Anne E. Hughes

Stephen A. Badger

Abstract

Background— Abdominal aortic aneurysm (AAA) is a common cardiovascular disease among older people and demonstrates significant heritability. In contrast to similar complex diseases, relatively few genetic associations with AAA have been confirmed. We reanalyzed our genome-wide study and carried thro...

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