Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer.

CJ, Allegra; G, Yothers; MJ, O'Connell; S, Sharif; LH, Colangelo; SH, Lopa; NJ, Petrelli; RM, Goldberg; JN, Atkins; TE, Seay; L, Fehrenbacher; S, O'Reilly; L, Chu; CA, Azar; N, Wolmark

doi:10.1200/jco.2009.21.9220

Public

Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer.

Shared by NobleBlocks on May 4, 2009 • 12:00 AM UTC

Authors:

Allegra CJ

Yothers G

O'Connell MJ

Abstract

<h4>Purpose</h4>The National Surgical Adjuvant Breast and Bowel Project C-08 trial was designed to investigate the safety and effectiveness of adding bevacizumab to modified infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX) 6 regimen for the adjuvant treatment of patients with stage II o...

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