Personalized oncology through integrative high-throughput sequencing: a pilot study.

Roychowdhury, Sameek; K Iyer, Matthew; R Robinson, Dan; J Lonigro, Robert; Wu, Yi-Mi; Cao, Xuhong; Kalyana-Sundaram, Shanker; Sam, Lee; Alejandro Balbin, O; J Quist, Michael; Barrette, Terrence; Everett, Jessica; Siddiqui, Javed; P Kunju, Lakshmi; Navone, Nora; C Araujo, John; Troncoso, Patricia; J Logothetis, Christopher; W Innis, Jeffrey; C Smith, David; D Lao, Christopher; Y Kim, Scott; Scott Roberts, J; B Gruber, Stephen; J Pienta, Kenneth; Talpaz, Moshe; M Chinnaiyan, Arul

doi:10.1126/scitranslmed.3003161

Public

Personalized oncology through integrative high-throughput sequencing: a pilot study.

Shared by NobleBlocks on Nov 30, 2011 • 12:00 AM UTC

Authors:

Sameek Roychowdhury

Matthew K Iyer

Dan R Robinson

Abstract

Individual cancers harbor a set of genetic aberrations that can be informative for identifying rational therapies currently available or in clinical trials. We implemented a pilot study to explore the practical challenges of applying high-throughput sequencing in clinical oncology. We enrolled patie...

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