Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders

Tennoune, N.; Tennoune, N.; Chan, P.; Breton, J.; Breton, J.; Legrand, R.; Legrand, R.; Chabane, Y.; Chabane, Y.; Akkermann, K.; Järv, Anu; Ouelaa, W.; Ouelaa, W.; Takagi, Kuniko; Takagi, Kuniko; Ghouzali, Ibtissem; Ghouzali, Ibtissem; Francois, M.; Francois, M.; Lucas, N.; Lucas, N.; Bôle-Feysot, C.; Bôle-Feysot, C.; Pestel-Caron, M.; D. Rego, J.; Vaudry, D.; Harro, J.; Dé, E.; Dé, E.; Déchelotte, P.; Déchelotte, P.; Fetissov, S.; Fetissov, S.

doi:10.1038/tp.2014.98

Public

Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders

Shared by NobleBlocks on Oct 1, 2014 • 12:00 AM UTC

Authors:

N. Tennoune

P. Chan

Abstract

The molecular mechanisms at the origin of eating disorders (EDs), including anorexia nervosa (AN), bulimia and binge-eating disorder (BED), are currently unknown. Previous data indicated that immunoglobulins (Igs) or autoantibodies (auto-Abs) reactive with α-melanocyte-stimulating hormone (α-MSH) ar...

Subject

Biology

Medicine

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