Identification of Novel Genes Coding for Small Expressed RNAs

In Caenorhabditis elegans , lin-4 and let-7 encode 22- and 21-nucleotide (nt) RNAs, respectively, which function as key regulators of developmental timing. Because the appearance of these short RNAs is regulated during development, they are also referred to as small temporal RNAs (stRNAs). We show t... View More