A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise.

W, Aoi; Y, Naito; T, Takagi; Y, Tanimura; Y, Takanami; Y, Kawai; K, Sakuma; LP, Hang; K, Mizushima; Y, Hirai; R, Koyama; S, Wada; A, Higashi; S, Kokura; H, Ichikawa; T, Yoshikawa

doi:10.1136/gutjnl-2011-300776

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A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise.

Shared by NobleBlocks on Jul 31, 2012 • 12:00 AM UTC

Authors:

Aoi W

Naito Y

Takagi T

Abstract

<h4>Objective</h4>Several epidemiological studies have shown that regular exercise can prevent the onset of colon cancer, although the underlying mechanism is unclear. Myokines are secreted skeletal muscle proteins responsible for some exercise-induced health benefits including metabolic improvement...

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