Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir.

N, Leung; CY, Peng; HW, Hann; J, Sollano; J, Lao-Tan; CW, Hsu; L, Lesmana; MF, Yuen; L, Jeffers; M, Sherman; A, Min; K, Mencarini; U, Diva; A, Cross; R, Wilber; J, Lopez-Talavera

doi:10.1002/hep.22658

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Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir.

Shared by NobleBlocks on Jan 1, 2009 • 12:00 AM UTC

Authors:

Leung N

Peng CY

Hann HW

Abstract

<h4>Unlabelled</h4>This study was undertaken to compare the early antiviral activity and viral kinetic profiles of entecavir (ETV) versus adefovir (ADV) in hepatitis B e antigen positive nucleoside-naïve adults with chronic hepatitis B (CHB). Sixty-nine nucleoside-naïve CHB patients with baseline HB...

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