Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value

Marisa, L.; de Reyniès, A.; Duval, A.; Selves, J.; Gaub, M.; Vescovo, Laure; Étienne-Grimaldi, M.; Schiappa, R.; Guenot, D.; Ayadi, M.; Kirzin, S.; Chazal, M.; Fléjou, J.; Benchimol, D.; Berger, A.; Lagarde, A.; Pencreach, E.; Piard, F.; Elias, D.; Parc, Y.; Olschwang, S.; Milano, G.; Laurent-Puig, P.; Boige, V.

doi:10.1371/journal.pmed.1001453

Public

Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value

Shared by NobleBlocks on May 1, 2013 • 12:00 AM UTC

Authors:

L. Marisa

A. de Reyniès

A. Duval

Abstract

Background Colon cancer (CC) pathological staging fails to accurately predict recurrence, and to date, no gene expression signature has proven reliable for prognosis stratification in clinical practice, perhaps because CC is a heterogeneous disease. The aim of this study was to establish a comprehen...

Subject

Medicine

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