A Comparison of Oral Ondansetron and Intravenous Granisetron for the Prevention of Nausea and Emesis Associated with Cisplatin‐Based Chemotherapy

I. Spector, Jesse; P. Lester, Eric; Chevlen, Eric; F. Sciortino, David; H. Harvey, Jim; Whaley, William; Madajewicz, Stefan; Isaacs, Randi; D. Homesley, Howard; Yee, Sharon; Beck, Thomas; Simon Tchekmedyian, N.; H. Crawford, Karen; Ames, Michael; R. Creed, Mary; and S3AA3007 Study Group, S3AA3004

doi:10.1634/theoncologist.3-6-432

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A Comparison of Oral Ondansetron and Intravenous Granisetron for the Prevention of Nausea and Emesis Associated with Cisplatin‐Based Chemotherapy

Published in The Oncologist • Dec 1, 1998

Authors:

Jesse I. Spector

Eric P. Lester

Eric Chevlen

Abstract

PURPOSE: To compare the efficacy and safety of oral ondansetron with i.v. granisetron each given as a single dose prior to administration of highly emetogenic cisplatin chemotherapy. PATIENTS AND METHODS: Chemotherapy-naive patients with histologically confirmed malignancies were randomized to recei...

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Open Access

Subject

Ondansetron

Granisetron

Medicine

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