A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection.

MJ, Newport; CM, Huxley; S, Huston; CM, Hawrylowicz; BA, Oostra; R, Williamson; M, Levin

doi:10.1056/nejm199612263352602

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A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection.

Shared by NobleBlocks on Dec 1, 1996 • 12:00 AM UTC

Authors:

Newport MJ

Huxley CM

Huston S

Abstract

<h4>Background</h4>Genetic differences in immune responses may affect susceptibility to mycobacterial infection, but no specific genes have been implicated in humans. We studied four children who had an unexplained genetic susceptibility to mycobacterial infection and who appeared to have inherited ...

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