Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl.

MH, Jia; RA, Larossa; JM, Lee; A, Rafalski; E, Derose; G, Gonye; Z, Xue

doi:10.1152/physiolgenomics.2000.3.2.83

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Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl.

Shared by NobleBlocks on Aug 9, 2000 • 12:00 AM UTC

Authors:

Jia MH

Larossa RA

Lee JM

Abstract

The expression pattern of 1,529 yeast genes in response to sulfometuron methyl (SM) was analyzed by DNA microarray technology. SM, a potent herbicide, inhibits acetolactate synthase, a branched-chain amino acid biosynthetic enzyme. Exposure of yeast cells to 0.2 microg/ml SM resulted in 40% growth i...

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