Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition.

S, Blott; JJ, Kim; S, Moisio; A, Schmidt-Küntzel; A, Cornet; P, Berzi; N, Cambisano; C, Ford; B, Grisart; D, Johnson; L, Karim; P, Simon; R, Snell; R, Spelman; J, Wong; J, Vilkki; M, Georges; F, Farnir; W, Coppieters

doi:10.1093/genetics/163.1.253

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Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition.

Shared by NobleBlocks on Jan 1, 2003 • 12:00 AM UTC

Authors:

Blott S

Kim JJ

Moisio S

Abstract

We herein report on our efforts to improve the mapping resolution of a QTL with major effect on milk yield and composition that was previously mapped to bovine chromosome 20. By using a denser chromosome 20 marker map and by exploiting linkage disequilibrium using two distinct approaches, we provide...

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