Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

Zampetaki, Anna; Kiechl, Stefan; Drozdov, Ignat; Willeit, Peter; Mayr, Ursula; Prokopi, Marianna; Mayr, Agnes; Weger, Siegfried; Oberhollenzer, Friedrich; Bonora, Enzo; Shah, Ajay; Willeit, Johann; Mayr, Manuel

doi:10.1161/circresaha.110.226357

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Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

Shared by NobleBlocks on Sep 17, 2010 • 12:00 AM UTC

Authors:

Anna Zampetaki

Stefan Kiechl

Ignat Drozdov

Abstract

Rationale: MicroRNAs (miRNAs) have been implicated in the epigenetic regulation of key metabolic, inflammatory, and antiangiogenic pathways in type 2 diabetes (DM) and may contribute to common disease complications. Objective: In this study, we explore plasma miRNA profiles in patients with DM. Meth...

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