Comparative immunogenicity and efficacy of 13-valent and 7-valent pneumococcal conjugate vaccines in reducing nasopharyngeal colonization: a randomized double-blind trial.

R, Dagan; S, Patterson; C, Juergens; D, Greenberg; N, Givon-Lavi; N, Porat; A, Gurtman; WC, Gruber; DA, Scott

doi:10.1093/cid/cit428

Public

Comparative immunogenicity and efficacy of 13-valent and 7-valent pneumococcal conjugate vaccines in reducing nasopharyngeal colonization: a randomized double-blind trial.

Shared by NobleBlocks on Jun 26, 2013 • 12:00 AM UTC

Authors:

Dagan R

Patterson S

Juergens C

Abstract

<h4>Background</h4>The 13-valent pneumococcal conjugate vaccine (PCV13) was licensed to replace the 7-valent pneumococcal conjugate vaccine (PCV7) based on serological noninferiority criteria. To date no randomized PCV13 pediatric trial has included clinical endpoints.<h4>Methods</h4>This randomized...

Subject

Immunogenicity

Pneumococcal Conjugate Vaccine

S. Pneumoniae

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