Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project.

MA, Pfeffer; A, Keech; FM, Sacks; SM, Cobbe; A, Tonkin; RP, Byington; BR, Davis; CP, Friedman; E, Braunwald

doi:10.1161/01.cir.0000017634.00171.24

Public

Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project.

Shared by NobleBlocks on May 1, 2002 • 12:00 AM UTC

Authors:

Pfeffer MA

Keech A

Sacks FM

Abstract

<h4>Background</h4>Therapeutic decisions regarding pharmacological therapy should be based on safety and tolerability as well as efficacy data. Clinical trials designed to assess efficacy are often insufficiently powered to generate reliable safety data.<h4>Methods and results</h4>The West of Scotla...

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