Interleukin-18 regulates both Th1 and Th2 responses.

K, Nakanishi; T, Yoshimoto; H, Tsutsui; H, Okamura

doi:10.1146/annurev.immunol.19.1.423

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Interleukin-18 regulates both Th1 and Th2 responses.

Shared by NobleBlocks on Jan 1, 2001 • 12:00 AM UTC

Authors:

Nakanishi K

Yoshimoto T

Tsutsui H

Abstract

Although interleukin-18 is structurally homologous to IL-1 and its receptor belongs to the IL-1R/Toll-like receptor (TLR) superfamily, its function is quite different from that of IL-1. IL-18 is produced not only by types of immune cells but also by non-immune cells. In collaboration with IL-12, IL-...

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