Changes in the ER, PgR, HER2, p53 and Ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis.

R, Nishimura; T, Osako; Y, Okumura; R, Tashima; Y, Toyozumi; N, Arima

doi:10.1186/1477-7819-9-131

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Changes in the ER, PgR, HER2, p53 and Ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis.

Shared by NobleBlocks on Oct 17, 2011 • 12:00 AM UTC

Authors:

Nishimura R

Osako T

Okumura Y

Abstract

<h4>Background</h4>In breast cancer, ER/PgR, HER2, and Ki-67 are important biological markers for predicting prognosis and making effective treatment decisions. In addition, changes in markers due to relapse are also clinically experienced; however, the frequency and clinical significance are still ...

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