Immunochemical evidence for protein abnormalities in platelets from patients with Glanzmann's thrombasthenia and Bernard-Soulier syndrome.

I, Hagen; A, Nurden; OJ, Bjerrum; NO, Solum; J, Caen

doi:10.1172/jci109719

Public

Immunochemical evidence for protein abnormalities in platelets from patients with Glanzmann's thrombasthenia and Bernard-Soulier syndrome.

Shared by NobleBlocks on Mar 1, 1980 • 12:00 AM UTC

Authors:

Hagen I

Nurden A

Bjerrum OJ

Abstract

Crossed immunoelectrophoresis of Triton X-100 solubilized proteins from normal and abnormal platelets was performed with rabbit antibodies raised against normal platelets. In Bernard-Soulier platelets protein 13 was not detected, and neither the amphiphilic (probably GP Ib) nor the hydrophilic (glyc...

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