The organization, promoter analysis, and expression of the human PPARgamma gene.

Fajas, L; Auboeuf, D; Raspé, E; Schoonjans, K; M Lefebvre, A; Saladin, R; Najib, J; Laville, M; C Fruchart, J; Deeb, S; Vidal-Puig, A; Flier, J; R Briggs, M; Staels, B; Vidal, H; Auwerx, J

doi:10.1074/jbc.272.30.18779

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The organization, promoter analysis, and expression of the human PPARgamma gene.

Shared by NobleBlocks on Jul 25, 1997 • 12:00 AM UTC

Authors:

L Fajas

D Auboeuf

E Raspé

Abstract

PPARgamma is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of the human PPARgamma cDNA and gene was determined, and its promoters and tissue-specific expression were functionally characterized. Similar to the mouse, two PPAR isoforms, PPARgamma1 and PPARgamma2, wer...

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