Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes.

Motohashi, Yoshiko; Yamada, Satoru; Yanagawa, Tatsuo; Maruyama, Taro; Suzuki, Ryuji; Niino, Masaaki; Fukazawa, Toshiyuki; Kasuga, Akira; Hirose, Hiroshi; Matsubara, Koichi; Shimada, Akira; Saruta, Takao

doi:10.1210/jc.2002-021881

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Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes.

Shared by NobleBlocks on Jul 1, 2003 • 12:00 AM UTC

Authors:

Yoshiko Motohashi

Satoru Yamada

Tatsuo Yanagawa

Abstract

Type 1 diabetes mellitus is recognized as a T-cell-mediated autoimmune disease. Vitamin D compounds are known to suppress T-cell activation by binding to the vitamin D receptor (VDR); and thus, VDR gene polymorphisms may be related to T-cell-mediated autoimmune diseases. We, therefore, investigated ...

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