Distinctive expression and function of four GSDM family genes (GSDMA‐D) in normal and malignant upper gastrointestinal epithelium

Saeki, Norihisa; Usui, Takebumi; Aoyagi, Kazuhiko; Ho Kim, Dal; Sato, Megumi; Mabuchi, Tomoko; Yanagihara, Kazuyoshi; Ogawa, Kenji; Sakamoto, Hiromi; Yoshida, Teruhiko; Sasaki, Hiroki

doi:10.1002/gcc.20636

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Distinctive expression and function of four GSDM family genes (GSDMA‐D) in normal and malignant upper gastrointestinal epithelium

Shared by NobleBlocks on Dec 2, 2008 • 12:00 AM UTC

Authors:

Norihisa Saeki

Takebumi Usui

Kazuhiko Aoyagi

Abstract

Abstract Gasdermin ( GSDM or GSDMA ), expressed in the upper gastrointestinal tract but frequently silenced in gastric cancers (GCs), regulates apoptosis of the gastric epithelium. It has three human homologs, GSDMB, GSDMC , and GSDMD ( GSDM family) and they are considered to be involved in the regu...

Distinctive expression and function of four <i>GSDM</i> family genes (<i>GSDMA‐D</i>) in normal and malignant upper gastrointestinal epithelium

Abstract

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