ジャガイモの履歴書 : 南アメリカ~ ヨーロッパ~日本
Published in Nucleic Acids Research • Mar 26, 2001
Authors:
前山 和彰
Abstract
Mammalian DNA methyltransferase 1 (DNMT1) is essential for maintaining DNA methylation patterns after cell division. Disruption of DNMT1 catalytic activity results in whole genome cytosine demethylation of CpG dinucleotides, promoting severe dysfunctions in somatic cells and during embryonic develop...
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