Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

Lener, T.; Gimona, M.; Aigner, L.; Börger, V.; Buzás, E.; Camussi, G.; Chaput, N.; Chatterjee, D.; Court, F.; D. del Portillo, H.; O’Driscoll, L.; Fais, S.; Falcón-Pérez, J.; Felderhoff‐Mueser, U.; Fraile, L.; Gho, Y.; Görgens, Andre; C. Gupta, Ramesh; Hendrix, A.; Hermann, D.; Hill, A.; Hochberg, F.; Horn, P.; D. de Kleijn, D.; Kordelas, L.; Kramer, B.; Krämer-Albers, Eva-Maria; Laner-Plamberger, S.; Laitinen, S.; Leonardi, T.; Lorenowicz, M.; Lim, S.; Lötvall, J.; Maguire, C.; Marcilla, A.; Nazarenko, I.; Ochiya, T.; Patel, T.; Pedersen, S.; Pocsfalvi, G.; Pluchino, S.; Quesenberry, P.; Reischl, I.; Rivera, F.; Sanzenbacher, R.; Schallmoser, K.; Slaper-Cortenbach, I.; Strunk, D.; Tonn, T.; Vader, P.; W. van Balkom, B.; Wauben, M.; E. Andaloussi, S.; Théry, C.; Rohde, E.; Giebel, B.

doi:10.3402/jev.v4.30087

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Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

Shared by NobleBlocks on Jan 1, 2015 • 12:00 AM UTC

Authors:

Thomas Lener

Mario Gimona

Ludwig Aigner

Abstract

Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different cell types and participate in physiological and pathophysiological processes. EVs mediate intercellular communication as cell‐derived extracellular signalling organelles that transmit specific information fro...

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