A Synthesis of 1H-Indazoles via a Cu(OAc)2-Catalyzed N-N Bond Formation.

CY, Chen; G, Tang; F, He; Z, Wang; H, Jing; R, Faessler

doi:10.1021/acs.orglett.6b00611

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A Synthesis of 1H-Indazoles via a Cu(OAc)2-Catalyzed N-N Bond Formation.

Shared by NobleBlocks on Mar 18, 2016 • 12:00 AM UTC

Authors:

Chen CY

Tang G

He F

Abstract

A facile synthesis of 1H-indazoles featuring a Cu(OAc)2-catalyzed N-N bond formation using oxygen as the terminal oxidant is described. The reaction of readily available 2-aminobenzonitriles with various organometallic reagents led to o-aminoaryl N-H ketimine species. The subsequent Cu(OAc)2-catalyz...

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