Thrombotic thrombocytopenic purpura associated with clopidogrel.

CL, Bennett; JM, Connors; JM, Carwile; JL, Moake; WR, Bell; SR, Tarantolo; LJ, McCarthy; R, Sarode; AJ, Hatfield; MD, Feldman; CJ, Davidson; HM, Tsai

doi:10.1056/nejm200006153422402

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Thrombotic thrombocytopenic purpura associated with clopidogrel.

Shared by NobleBlocks on Jun 1, 2000 • 12:00 AM UTC

Authors:

Bennett CL

Connors JM

Carwile JM

Abstract

<h4>Background</h4>The antiplatelet drug clopidogrel is a new thienopyridine derivative whose mechanism of action and chemical structure are similar to those of ticlopidine. The estimated incidence of ticlopidine-associated thrombotic thrombocytopenic purpura is 1 per 1600 to 5000 patients treated, ...

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