Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase.

J, Yang; D, Yuan; T, Xing; H, Su; S, Zhang; J, Wen; Q, Bai; D, Dang

doi:10.1016/j.jgr.2016.03.007

Public

Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase.

Shared by NobleBlocks on Apr 5, 2016 • 12:00 AM UTC

Authors:

Yang J

Yuan D

Xing T

Abstract

<h4>Background</h4>Ginsenoside Rh2 (GRh2) is the main bioactive component in American ginseng, a commonly used herb, and its antitumor activity had been studied in previous studies. PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK), a serine/threonine protein kinase, is highly expre...

Subject

Apoptosis

Antitumor effect

Ginsenoside Rh2

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