Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors.

K, Leander; A, Mälarstig; Hooft FM, Van't; C, Hyde; ML, Hellénius; JS, Troutt; RJ, Konrad; J, Öhrvik; A, Hamsten; Faire U, de

doi:10.1161/circulationaha.115.018531

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Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors.

Shared by NobleBlocks on Feb 19, 2016 • 12:00 AM UTC

Authors:

Leander K

Mälarstig A

Van't Hooft FM

Abstract

<h4>Background</h4>The secreted protein proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising new target for lowering plasma low-density lipoprotein cholesterol and preventing cardiovascular disease (CVD). The relationship between circulating PCSK9 and incident CVD in the general popu...

Subject

Enzymes

Cardiovascular diseases

Biomarkers

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