Chondrogenic Effect of Intra‐articular Hypertonic‐Dextrose (Prolotherapy) in Severe Knee Osteoarthritis

Andrés Topol, Gastón; Ariel Podesta, Leandro; Dean Reeves, Kenneth; Mallma Giraldo, Marcia; L. Johnson, Lanny; Grasso, Raul; Jamín, Alexis; Clark, Tom; Rabago, David

doi:10.1016/j.pmrj.2016.03.008

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Chondrogenic Effect of Intra‐articular Hypertonic‐Dextrose (Prolotherapy) in Severe Knee Osteoarthritis

Shared by NobleBlocks on Apr 4, 2016 • 12:00 AM UTC

Authors:

Gastón Andrés Topol

Leandro Ariel Podesta

Kenneth Dean Reeves

Abstract

Abstract Background Dextrose injection is reported to improve knee osteoarthritis (KOA)−related clinical outcomes, but its effect on articular cartilage is unknown. A chondrogenic effect of dextrose injection has been proposed. Objective To assess biological and clinical effects of intra‐articular h...

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